CALL FOR PAPERS Neurobiology of Deep Brain Stimulation Blockade of in vitro ictogenesis by low-frequency stimulation coincides with increased epileptiform response latency
نویسندگان
چکیده
Toshiyuki Kano, Yuji Inaba, Margherita D’Antuono, Giuseppe Biagini, Maxime Levésque, and Massimo Avoli Montreal Neurological Institute and Departments of Neurology & Neurosurgery and Physiology, McGill University, Montreal, Quebec, Canada; Shinshu University, School of Medicine, Matsumoto, Japan; and Dipartimento di Scienze Biomediche, Metaboliche e Neuroscienze, Università di Modena e Reggio Emilia, Modena, Italy
منابع مشابه
Blockade of in vitro ictogenesis by low-frequency stimulation coincides with increased epileptiform response latency.
Low-frequency stimulation, delivered through transcranial magnetic or deep-brain electrical procedures, reduces seizures in patients with pharmacoresistant epilepsy. A similar control of ictallike discharges is exerted by low-frequency electrical stimulation in rodent brain slices maintained in vitro during convulsant treatment. By employing field and "sharp" intracellular recordings, we analyz...
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Epilepsy is the most common neurological disease with no definitive method in treatment. Notably, the main way to treat and control epileptic seizures is drug therapy. However, about 20-30% of patients with epilepsy are drug resistant and require other therapeutic manners. Deep brain stimulation is a new therapeutic strategy for these patients. Conspicuously, there are no clear answers for basi...
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Background: The interaction between antiepileptic drugs and brain electrical stimulation is a potential therapy to control of seizures in patient with pharmacoresistance to drugs. So, the aim of present study was designed to determine the effect of a sub effective dose of sodium valproate combined with low-frequency electrical stimulation during kindling. Material and Methods: One tripolar ele...
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